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The medical community has invested more than 25 years into studying the effects of HGH on muscle development, fat loss, brain function, sexual health and aging.

Clinical studies have repeatedly supported the claims you’ll hear made by bodybuilders of all levels all around the world. There is significant evidence showing the use of HGH supplementation for six months or longer can help you:

  • Stack on more lean muscle
  • Reduce your overall body fat composition
  • Pump up the intensity of your workouts
  • Noticeably increase the results you get from the same workouts
  • Enjoy faster recovery times

Here’s just a small sample of the medical studies that have been done to demonstrate these points. They show the powerful effects of HGH under different conditions, whether it is introduced subcutaneously or through natural secretion via precursors:


Men who supplemented HGH for six months using injections experienced:

An 8.8% increase in lean body mass, a 14.4% decrease in adipose-tissue mass, i.e. fat, and a 7.1% increase in skin thickness.

The effects of six months of HGH on lean body mass and adipose- tissue were equivalent in magnitude to the changes incurred during 10 to 20 years of aging.

Source: N Engl J Med 1990; 323:1-6July 5, 1990

Effects of Human Growth Hormone in Men over 60 Years Old »

Growth hormone given for six months to healthy older men with well-preserved functional abilities increased lean tissue mass and decreased fat mass.

Source: Annals of Internal Medicine April 15, 1996, vol. 124 no. 8

Growth Hormone Replacement in Healthy Older Men Improves
Body Composition But Not Functional Ability »

Growth hormone supplementation by injection further enhances gains in total and appendicular lean mass, muscle strength, and aerobic endurance with significant reductions in whole-body and trunk fat.

Source: The Journal of Clinical Endocrinology & Metabolism June 1,
2009 vol. 94 no. 6 1991-2001, 708-716.

Testosterone and Growth Hormone Improve Body
Composition and Muscle Performance in Older Men »

Growth hormone significantly reduces fat.

Source: The Journal of Clinical Endocrinology & Metabolism

Effects of Once-Weekly Sustained-Release Growth Hormone: A Double-Blind, Placebo-Controlled Study in Adult Growth Hormone Deficiency »

Higher levels of growth hormone (GH) are released with more intense training.

Source: J Sports Med Phys Fitness. 2011 Jun;51(2):322-8.

Acute effect of resistance training volume on
hormonal responses in trained men. »

HGH replacement injections increase lean body mass.

Source: J Clin Endocrinol 1996;45:399-405 &Clin Endocrinol (Oxf)


GH replacement therapy for 10 years provided protection from most of the normal age-related decline in muscle performance and neuromuscular function.

Source: Eur J Endocrinol August 1, 2010 163 207-215

Muscle strength in elderly adults with GH
deficiency after 10 years of GH replacement »

Some orally active compounds could offer attractive alternatives to HGH injections.

Source: Drug Discovery Today, Volume 4, Issue 11, 1, November 1999, Pages 497-506

Growth hormone secretagogues: Recent advances and applications »

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It may reverse or prevent some of these inevitable effects of aging.

Source: Psychoneuroendocrinology, Volume 17, Issue 4, August 1992,
Pages 327-333.

Growth hormone secretagogues:
recent advances and applications »

GH secretagogues could rejuvenate GH and IGF-1 Levels.

Source: Am J Physiol Endocrinol Metab. 2007 Nov; 293(5):E1140-52.


Dr. Chein of the Life Extension Institute studied 202 patients that he treated with HGH. Patients reported improvement in the following areas:

  • » Healing of Other Injuries – 61%
  • » Wrinkle Disappearance – 61%
  • » Overall Life Outlook – 78%
  • » Emotional Stability – 67%
  • » Exercise Tolerance – 81%
  • » New Hair Growth – 38%
  • » Healing Capacity – 71%
  • » Skin Thickness – 68%
  • » Skin Elasticity – 71%
  • » Back Flexibility – 83%

Source: The Chein Study by Dr. Leon Cass Terry, M.D., Ph.D. at the Medical College of Wisconsin, and Dr. Edmund Chein, M.D. at the Palm Springs Life Extension Institute.


HGH is beneficial for cardiac and renal function, and thyroid hormone and bone metabolism. It is also beneficial for sweat secretion, psychological well-being, and total and regional fuel metabolism.

Source: Dr. Jorgensen and Dr. Christian of Copenhagen, Denmark European Journal of Endocrinology, 1994


HGH infusions promote speedy recovery from trauma.

Source: AZ: May 1992, Journal of Surgery. Vol 111, 495-502

“Daily administration of human growth hormone in the first week after
trauma would enhance the metabolic status… resulting in reduced morbidity
and earlier discharge from the hospital.” – Drs. Ramias, Shamos, & Schiller of St. Joseph Hospital Medical Center, Phoenix, AZ

Drs. Ramias, Shamos, & Schiller of St. Joseph Hospital Medical Center,
Phoenix, AZ


Oral HGH secretagogues may improve body composition and physical function.

Source: White et al. J Clin Endocrinol Metab.2009; 0: jc.2008-0632v1

Effects of an Oral Growth Hormone
Secretagogue in Older Adults »

Stimulating HGH production could reduce the loss of muscle mass, strength and exercise capacity.

Source: Clin Interv Aging. 2008;3(1):121-9; Hersch EC, Merriam GR.

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